Some heavy hitters this week including a 4-hour marathon with Lex Fridman and Robert Breedlove on the fundamental basis of our reality, economy and the future of money (top 5 podcast of the year), as well as 2 hours with the smartest and bravest chemist in the psychedelics words – Hamilton Morris.

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Up This Week:

 
Not every great company comes from tech and needs venture funding. In this member's only post, Emily Hyland (cofounder of Pizza Loves Emily) shares advice on how she helped start and grow her famous pizza restaurant, business lessons she learned along the way, and how to recover after a divorce.
 

 
 

Wisdom

1/ 3 Forms of Pragmatic Truth: - Robert Breedlove
  • Price: Subjective demands of humans against the objective supply of resources
  • Tools and innovations: Entrepreneurs experiment to profitably satisfy demands and consumers are sovereign in their demands
  • Virtue: Lying is energy inefficient, akin to creating and maintaining a fork of reality.
2/ Starting a Company with Your Spouse is a HUGE Risk: You have to be able to separate your business and personal life even if you work together. Since Emily and Matthew were working long days almost everyday, they didn’t have much time to work on their marriage and they slowly started to drift apartEmily Hyland

3/ The Largest Living Organism in the World: A mycelial mat at about 2,200 acres in size (about 665 football fields!)Paul Stamets [Throw back]

4/ If Your Child is an A$$hole it’s Your Fault: Children learn about cause and effect – A bad father, for example, teaches a child that 50% of people are going to treat them badly – Adam Lane Smith

5/ The Single Greatest Predictor of Extra-Marital Sex: Pre-marital sex – Adam Lane Smith

Health

6/ Future of Psychedelics: lots of big players, more money behind it, IP lawsuits, research centers, for-profit sector, university involvement, viable field as career path – Hamilton Morris

7/ Beware The Toad: 5-MeO-DMT is pharmacologically, chemically, and psychologically distant from psychedelics (including DMT) – you become largely unresponsive at high doses, mimicking more of a near-death experience – Hamilton Morris

8/ Xenon Gas, The Noble Anesthetic: Xenon is a perfect anesthetic: it cannot be metabolized, it can be recycled indefinitely, it’s potent, patients recover rapidly, no known toxicity – Hamilton Morris

9/ When Eating Clean Can Leave Your Lacking: Some “clean” diets can interfere with thyroid functions by disrupting iodine pathway – plant-rich hard diets make it challenging to get enough L-tyrosine; with a carnivore diet it is hard to get enough iodineAndrew Huberman, PhD

10/ Grow Your Growth Hormone: Lifestyle activities to increase growth hormone: (1) increase slow wave/deep sleep; (2) exercise 60-75 minutes – but not working to failure which increases cortisol; (3) sauna at 176-210F for 20-30 minutes – increase growth hormone 16 fold; (4) supplement with arginine, ornithine, or L-citrulline Andrew Huberman, PhD
 
Wealth

11/ Inflation is Theft and Violence: “You can just print more money that everyone else is forced to sacrifice their time and energy to obtain”. Inflationary money amplifies the perception of scarcity and results in increased fear, combativeness, and violence in a society. Additionally, it has a corrosive effect on social morality, encouraging short term thinking and selfish behavior. Robert Breedlove

12/ The First Communist: The first-ever capitalist was a caveman who dug a hole to protect himself from the elements. The first communist then decided he has a claim over the fruits of this man’s labor, and violently took over the plot for his own use. Robert Breedlove
  • The 1848 manifesto of the communist party mandates exclusive state control over cash and credit. In other words, central banks are Marxist institutions

13/ Founderitis: When a founder gets to attached to their original idea and prevents their company from evolving and growing Emily Hyland

14/ Sorry Vitalik/Ether: Proof of Stake is inherently centralizing, think of the old Mathew principle: “For to everyone who has, more shall be given, and he will have an abundance; but from the one who does not have, even what he does have shall be taken away” Robert Breedlove

 
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Podcast Notes · Home Is Where The Headphones Are · Chappaqua, New York 10514 · USA